Enhanced UV Inactivation of Adenoviruses under Polychromatic UV Lamps

Enhanced UV inactivation of adenoviruses under polychromatic UV lamps.

Adenovirus is recognized as the most UV-resistant waterborne pathogen of concern to public health microbiologists. The U.S. EPA has stipulated that a UV fluence (dose) of 186 mJ cm(-2) is required for 4-log inactivation credit in water treatment. However, all adenovirus inactivation data to date published in the peer-reviewed literature have been based on UV disinfection experiments using UV ir...

Endotoxin inactivation in water by using medium-pressure UV lamps.

Deionized water was spiked with various concentrations of endotoxin and exposed to UV irradiation from medium-pressure UV lamps to assess endotoxin inactivation. It was found that endotoxin inactivation was proportional to the UV dose under the conditions examined. The inactivation rate was determined to be approximately 0.55 endotoxin unit/ml per mJ/cm(2) of irradiation delivered.

Spectral Distribution of UV Light During Aging of Medium Pressure UV Lamps

As part of a project to validate a UV reactor for disinfection of drinking water, the germicidal output of four medium pressure lamps housed in a continuously operating reactor was followed as a function of time. Spectra were measured monthly and were used in conjunction with radiometer readings to calculate germicidal fluence rates (using DNA absorbance weighting) at the radiometer sensor posi...

Disinfection Efficiency and Dose Measurement of Polychromatic UV Light

UV disinfection of adenoviruses: molecular indications of DNA damage efficiency.

Adenovirus is a focus of the water treatment community because of its resistance to standard, monochromatic low-pressure (LP) UV irradiation. Recent research has shown that polychromatic, medium-pressure (MP) UV sources are more effective than LP UV for disinfection of adenovirus when viral inactivation is measured using cell culture infectivity assays; however, UV-induced DNA damage may be rep...